KAIST researchers have designed a therapy that instead of killing cancer cells, reverts them to a harmless state like normal cells. This not only significantly reduces side effects but can also become a long-term and effective solution.

The research team studied the oncogenesis process (in which normal cells lose their differentiation and become cancer cells) and developed a digital twin gene network using advanced simulation tools. With this, they identified molecular switches that can take cancer cells back to their original state. When these switches were applied to colon cancer cells, the cells showed normal-like behavior. The success of this approach was also proven through cellular and animal studies.

read next….